Mayo B Samples Come Back Negative

by Rant on October 22, 2007 · 19 comments

in Doping in Sports, Floyd Landis, Iban Mayo, Tour de France

In case you haven’t already heard, Iban Mayo’s B sample tests came back negative today. The tests were a counter-analysis of a sample taken during the Tour de France that allegedly tested positive for EPO when initially analyzed at France’s anti-doping laboratory (LNDD). It took about two months for the labs involved in the B sample tests to reach their conclusion– about half the time it took a certain arbitration panel to reach their decision in the Floyd Landis case — but still too long to reach a conclusion. Somewhere in Spain, Mayo must be breathing a few sighs of relief. The last two months could hardly have easy.

As the Guardian reports:

“It was a very bad experience because I didn’t understand what was happening…. but everything has turned out as I expected,” Mayo was quoted as saying on the Web site of Spanish sports daily Marca (www.marca.com)

The 30-year-old Saunier Duval rider, who was subsequently suspended by his team, failed the test on the July 24 rest day of this year’s Tour. He finished the race in 16th place overall.

Spanish media said that the Spanish Cycling Federation (RFEC) had told Mayo’s lawyer that the ‘B’ test had been negative.

A spokesman for Mayo’s team, Saunier Duval, said that they had not yet been officially informed of the test results.

The news of Mayo’s result is a good illustration of one of the key problems with the way the current ProTour “ethics policy” and WADA’s anti-doping procedures conflict with each other. In the end, the riders wind up getting screwed.

On the one hand, the UCI’s ProTour ethics policy requires that teams suspend a rider when an A sample comes back “non-negative.” On the other hand, WADA’s rules guarantee an athlete’s privacy until the B sample comes back confirming an A sample’s results. Under WADA’s rules, we would not have heard about Mayo’s positive test unless there was confirmation of the results on counter-analysis.

But under the ProTour ethics rules, Mayo had to be suspended once the initial “positive” results of his tests came back. With any rider, suddenly being unavailable to race would seem odd. With a rider as well-known as Mayo, a sudden disappearance from racing without explanation would be taken by many to indicate his being caught up in a doping case. There aren’t too many ways to keep news of a rider’s A sample returning a positive anti-doping test quiet. Especially with the leakiness of certain labs and other organizations.

Under ProTour rules, it’s virtually a guarantee that the public will know about a rider’s positive result before the B sample comes back. Once news leaks out that a rider has been suspended, it wouldn’t take a genius to guess why. And given the tenor of the times, it’s virtually guaranteed that many will conclude the rider must be a doper, long before such a conclusion would be warranted. How many people assumed Mayo was guilty of using EPO long before the B sample results came back negative? How many still think he did it?

For the last two+ months, Mayo has been unable to race. No race, no prize money, no income — unless his team decided to pay his salary while waiting for the B sample results. Regardless of being suspended with or without pay, imagine being sidelined and unable to do your job for so long, wondering whether you’ll be cleared and able to work again, or you’ll be charged with a doping offense.

In either case, it’s bad. Being suspended without pay (which happens in “real life,” too) puts the punishment before the verdict. Mayo, being a highly-paid cyclist, probably didn’t suffer too badly in a financial sense (although this scandal could have had consequences as far as sponsorships and endorsements goes). For others of lesser means, however, even a couple of months taken out of the cycling season could be devastating. For an average person, a two-month suspension from work without pay could wreak havoc on one’s finances.

From where I see it, there is nothing ethical about throwing someone out of work before the evidence is strong enough to warrant a conclusion of wrong-doing. That the evidence came from a lab which has become notorious for less than stellar work makes taking such action even more suspect. Only if there’s a doping case to answer — which there isn’t until either the athlete accepts the A sample results or the B sample results confirm the original finding — can suspending the athlete can be justified. Before then, the rider should be allowed to race. If there’s a doping case, and the rider is found guilty, appropriate punishment can (and should) occur. But not before.

Consider the difference between two cyclists accused of using synthetic testosterone in 2006. In Joe Papp’s case, he was able to keep competing until the results of the B sample counter-analysis came back. In Floyd Landis’ case, he was hung out to dry even before his team had received any official word of his test results. With the required suspension, followed by the required dismissal after the B sample results were announced, Landis was effectively suspended — not just by his team, but from competition entirely — just days after his Tour victory.

In most countries, there’s a concept of equal protection under the law. In the world of the UCI and WADA, there is no such equal protection. If the goal of WADA’s anti-doping efforts is to “harmonise” the system, then all athletes should be treated the same way when facing anti-doping charges. As it stands today, they’re not.

Another twist to the Mayo case is the fact that his B samples were tested in two other labs, rather than at LNDD. The University of Ghent, in Belgium, and at the Australian anti-doping lab. Interestingly, this is a WADA requirement (the testing at other labs, not the particular labs where Mayo’s tests were performed), as the EPO test is a difficult test to perform and properly interpret. The analysis at the different labs is at least partly responsible for the lengthy delay in getting Mayo’s B sample results.

Having B samples tested at other labs should occur for all types of tests, not just the especially tricky ones. That said, with those tests that are of greater difficulty, the certification process should be much more thorough. Given the stakes, labs should demonstrate a very high level of proficiency before being allowed to perform such tests. If that means there are fewer labs able to do so, so be it. If that makes for logistical problems for the anti-doping labs, so be it.

For the athletes, the stakes are extraordinarily high. One bad result and they could be out of a job. One problematic result on the part of an ADA’s lab techs, on the other hand, doesn’t have such great consequences for those conducting the tests. Which is why the labs should be held to higher standards. If it was your job on the line, wouldn’t you want to know that the labs were required to meet stringent certification standards? I’d hate to lose my job because the tests were improperly conducted by poorly trained staff.

Which is not to say that this was the case in LNDD’s analysis of Mayo’s A sample. Given some of the revelations about LNDD over the last few years, the Mayo result does raise additional questions about the lab and their certification to perform the work. Good results can be repeated equally well by other labs. Poor quality results cannot.

It’s a safeguard in the system that B sample analysis is required before charging an athlete with doping. It’s a safeguard that some (like Dick Pound) would toss away, on the theory (not yet proven) that the tests are so good that merely the A sample results should be enough to convict someone of doping.

Iban Mayo dodged a bullet today. It leaves me wondering, who will the first person be to apologize to him for having to sit out the Vuelta, the world championships and a host of other races? Who can make it up to him? What’s happened here should be a cautionary tale for those who make the rules. It’s time to rethink requiring the pros to sit out while awaiting their B sample results, or to rework the testing protocols to enable quicker results that will get innocent riders back on the road, and guilty riders punished sooner.

I have a hunch that the powers that be won’t notice or heed such a lesson. Instead, I can picture certain individuals crowing about how fair the system is. Or the same individuals saying, “Well, he got away this time. But next time …”

Iban Mayo, quoted in the Guardian, commented on what’s happened to him over the last couple of months:

“I have never stopped training, but psychologically I had a very bad time although people have helped me. I’ve got a year left on my contract with the team and I hope to complete it.”

“[S]ometimes you feel like [quitting] because there are so many injustices.

“The fans who like cycling don’t want to see this sort of thing happen.”

Exactly.

Larry October 23, 2007 at 7:00 am

Rant, there is a LOT to respond to in this post! But possibly the most important thing is, the testing of Mayo’s B sample may not be complete yet. There’s a report that, according to McQuaid at UCI, the B sample is going BACK to the LNDD for further testing! http://eurosport.yahoo.com/23102007/58/mayo-b-sample-re-analysed.html. This report also has McQuaid saying what I’ve heard elsewhere, that the B sample was tested at a second lab only because the LNDD was closed at the time the B sample had to be tested.

Larry October 23, 2007 at 7:59 am

Rant, here’s excepts from the latest VeloNews report. I’m not posting any personal comments on this new information until it’s straightened out, but there’s enough information here to cover a month’s worth of rants:

It seems Iban Mayo isn’t out of the woods yet after what initially appeared to be a “miracle” B-sample that came back negative and cleared the Spanish climber of doping allegations.

On Monday, the Spanish cycling federation shelved a potential two-year racing ban against the Saunier Duval-Prodir rider, who tested positive for EPO during the 2007 Tour de France. His lawyer and Spanish cycling authorities both confirmed the test results of the second, follow-up “B” sample are negative.

Officials from the UCI on Tuesday, however, insisted that follow-up tests of “B” samples aren’t completed yet and there’s more to be done before the once-mighty Basque is fully in the clear.

“The second sample is not negative,” UCI anti-doping coordinator Anne Gripper told AFP at Tuesday’s doping summit in Paris. “The analysis of it has not yet finished.”

There were some reports that labs botched the test, but Gripper insisted that testing methods between labs in France, where the “A” sample was tested, and follow-up tests in Belgium are not the same. Officials now want a second sample to be re-tested at the Chatenay-Malabry lab in France.

She said it would be another “five or six weeks” before the second round of tests is completed. Even if the follow-up tests are negative, the UCI said it might consider an appeal to the Court of Arbitration for Sport.

William Schart October 23, 2007 at 8:09 am

This is rather frightening. Are they going to keep testing things until they get ther result they want? The article Larry links raises some questions in my mind:

1. I had heard that the B test was done in 2 labs, Ghent and Australia, but McQ only mentions Ghent. Is this just a simple overlook on his part, or perhaps on the part of the reporter; was I mis-informed; or what?

2. Is there still remaining portion of the B sample, uncontaminated and undeteriorated, to do additional testing, or will this simply be a case of re-analyzing existing data?

3. If the Ghent (and possible other) tests were inconclusive, should not this be reason to drop the case? Does WADA rules address this situation? It seems to me that I have heard of cases being thrown out because the B sample had been contaminated or deteriorated and could not be reliably tested.

My guess is that LNDD will confirm its own results. We have the techs testimony that if at first they don’t get the results they want, they erase the original data and do things over until they get what they want. Mayo, you can kiss your career goodbye!

ddt240 October 23, 2007 at 8:30 am

I have a lot of comments that I would like to make about this, but I can sum it all up into one word. “Disgusted”

Rant October 23, 2007 at 8:33 am

Larry,

Just when you think a story is coming to an end, like a bad horror film, they throw a new, even scarier plot twist at you. Next year’s Halloween flick will be “Night of the Living Dope Tests.”

William,

Agreed. It’s very frightening. It’s been pretty widely reported that Mayo’s B sample was tested in both Ghent and Australia. So why McQuaid doesn’t mention the Aussie lab is beyond me. I, too, wonder just how much B sample remains and whether there’s enough to do further testing. And, like you, if the tests are inconclusive it should be case closed, no prosecution. LNDD’s lab techs may very well do just what you say. If at first you don’t get the data you want, erase and try again. Repeat until results achieved. If that’s how it plays out, Mayo’s in for a new, worse nightmare than he’s had up to now.

Morgan Hunter October 23, 2007 at 9:08 am

This just plain absurd! – How can the JUSTIFY sending it back to LNDD? – If TWO OTHER LABS TESTED IT – AND GOT DIFFERENT RESULTS FROM LNDD – wouldn’t this be the same “cheery-picking” that went on with Floyd’s case and the ARBs?

I can’t believe that “people are just going to take this – I have much more to comment – but I cannot – none of it is pc or printable in a legitimate blog!

I do have one suggestion – how about if we drown the whole lot of them?

austincyclist October 23, 2007 at 9:28 am

I’m assuming LNDD will of course back up their initial test and Mayo will be in the fire again.. Wonder when they’ll pull the other “B” samples from non-positive tests out of the woodwork for additional “confirmation”.

ludwig October 23, 2007 at 9:28 am

The short answer to all this is that the Spanish Federation is not by any means the final word on this. Keep in mind they cleared virtually every Spanish rider associated with Operation Puerto, but these riders (save Contador, Valverde, etc) were not allowed back into Pro Tour races. It’s no secret to anyone that the Spanish Federation is soft on doping and dominated by the doping DSes and doctors.

The UCI doesn’t win any points for transparency or straightforward deliberation (but then they have a history of cover-ups and white-washes anyway).

Rant October 23, 2007 at 9:45 am

Larry,

I’m going to have to wait until later to find the document, but from what I remember the confirmation by another lab is actually a part of WADA’s technical document regarding EPO tests. Unfortunately, the gateway at my office blocks access to WADA’s web site, so I won’t be able to track the document and specific passage down until this evening.

Ludwig,

One point to keep in mind, the B sample analyses were done at Ghent and in Australia, rather than in Barcelona. So while you’re right that the Spanish Federation is by far not the last word, there’s no vested interests in either lab as far as returning results that could be used to find him guilty or cover up a guilty finding.

susie b October 23, 2007 at 10:04 am

So, the original A test at LNDD took ~5 days. Results were told to the world a few days after the TDF ended. (Thanks to L’Equipe… 😉

Almost 3 MONTHS later, we read that 2 different Labs tested the B sample & are deemed negative. What happened here? Was there a fight about where they would be tested? Who got to decide? Was the sample WALKED to Belgium & sent on a 19th century Clipper ship to Oz? Or was a fight over who was to do the B testing the true hold-up? How long does that test really take? Do you need to ‘age’ the sample? 😉 And it’s about time the B test was done somewhere OTHER than where the A test occured. However, doesn’t it shock you they allowed it?

And now UCI wants LNDD to have ANOTHER go at the B sample. Which should take “5-6 weeks”. Again, 5-6 WEEKS. How were they able to whiz through it so fast during the Tour? Why would ANY test take 5-6 weeks? Or does it take a couple hours for the actual test & WEEKS for them to pore over the results & “interpret”? And why would the UCI want the LNDD to do the testing anyway? What’s in it for them? That is the chosen lab of the org trying to crush them – ASO.

Do you think it’s possible that the 1st LNDD test actually picked up Dynepo & accidentally flagged it as positive? Although, technically it should be on the prohibited list, correct? How often can WADA add to the Prohibted List? Only once/year? If a test can pick up on Dynepo, why ISN’T it on the list already? Although I thought the test for it wasn’t accurate.

One thing I KNOW – if it is proved that LNDD messed up Mayo’s EPO test, then every test LNDD has ever performed will come under suspicion. Which is GREAT for Floyd but the opposite of what ASO, UCI, USADA, WADA, & that French Anti-Doping org want. Are you kidding? THIS is their worst nightmare! Some of these people will do whatever so that THEIR version of the truth is the ‘official’ one. That 2nd Velo News article is right – Mayo better not be celebrating just yet.

I’m just hoping that the story we’ve read so far about Mayo’s test is like that little blurb about a ‘break-in at a DC hotel/office complex’ some 35 years sgo. And the LNDD is going DOWN. And Floyd will be riding again by next spring. But just who will be cycling journalism’s “Woodstein”?

Larry October 23, 2007 at 10:21 am

I want to gather facts before reaching any conclusions …

There have been a number of posts stating that Mayo’s B sample was sent to Australia after being tested at Ghent. However, all of these reports seem to stem from a single report by Spanish newspaper Diario Vasco. I can’t find any other confirmation that Mayo’s B sample was tested in Australia.

Diario Vasco may also be the sole source of the report that EPO B tests must be performed by two different labs. I can’t find this requirement anywhere either. Rant, I’ve looked at what I think is the current WADA technical document for EPO testing — it is at http://www.wada-ama.org/rtecontent/document/td2007epo_en.pdf. This TD requires two tests on an “A” sample to confirm a positive finding, but I don’t see anything there that mandates B tests to be peformed in two laboratories. I did find one quote from the famed Dr. Botre, stating that in close cases, WADA suggests that the lab ask for the opinion of a second lab before releasing positive EPO tests. http://www.iht.com/articles/2005/09/04/news/lance.php. But this quote goes back to 2005 and there’s nothing I see in the 2007 TD suggesting the need to test at 2 labs.

I’ll also point out that Marion Jones’ positive “A” and negative “B” finding for EPO were both performed at the UCLA lab. No other lab was mentioned in her EPO case. Her EPO testing was performed in 2006 — it’s possible, I suppose, that there’s a new rule out there requiring “B” tests to be performed in two labs, but I can’t find any such rule.

In the absence of anything specific, the general ISL requirement (I think it is paragraph 5.2.4.3.2.2) should govern. This says that the “B” Sample confirmation must be performed in the same Laboratory as the “A” Sample confirmation.

I’m concluding for the moment that the Mayo “B” test was performed at a single lab, in Ghent, and that the Ghent lab got involved because LNDD was closed for vacation at the time the “B” test was requested.

Morgan Hunter October 23, 2007 at 12:10 pm

I still think a good drowning would not hurt – my only concern is – does this make me into a doper?

Nice piece of investigating work Larry. Now I’ll have to be reading the info you provided. But it is worth it.

Susie B – Wow – Impressive AND humerus – I like the way your mind works. It would appear – that to get fastest results – all we have to do is put a deadline to be going on vacation and EVERYTHING is possible.

bill hue October 23, 2007 at 4:40 pm

I suspect the supposed “B” sample may not really be a “B” sample at all. Rather, there may be two “A”s, perhaps one urine and one blood or two separate urines from two different stages. The problem is that we don’t know the facts and they have not been revealed by any questioning by the same journallists who misuse the term “B” sample. Thus we are trying to create a fact set to fit the results we think we know. That is not an advisable way to come to any conclusion.

Larry October 23, 2007 at 5:03 pm

Bill, agreed! This is very frustrating for those of us who’d actually like to know what is going on. I’m a reasonable guy who always looks for the reasonable explanation, but sometimes it seems like the agencies who run cycling can do whatever the hell they want whenever the hell they want.

William Schart October 23, 2007 at 5:34 pm

The waters get muddier and muddier. If the Aussie lab was not involved, why the long time. I seem to recall that the Ghent testing was completed some time ago, but then as I recall that announcement was connected with the idea that it now was being send down under, so maybe that is suspect. Why one test should take so long to conduct is beyond me.

Regardless, we still have the situation where seemingly the confirmatory test (whether on a B sample, the original A sample or a second A sample) did not back up the original positive test. Whether the second test was truly negative, or simply inconclusive, should not that be enough?

There is one other possible explanation I can see: as some have mentioned, 2 confirming tests are needed; Ghent provided one, it might have been suggested that the Aussies do the other, but for some reason that was not done and now they are sending it back to LNDD for the second test. Maybe there aren’t that many labs qualified to do EPO testing, and after Ghent the others were busy.

Since it was well know that Mayo’s A sample had come back positive and that further testing was in the works, privacy was not much of an issue here. So why should not UCI be clear what is going on here? “These are the rules regarding EPO testing, it has to be done such and such a way, and after the Ghent results came back, there is further testing that needs to be done, so we are having LNDD doing this.” Or whatever legitimate explanation there is, if indeed there is a legitimate one.

Susie:

Even if Mayo is ultimately cleared, it doesn’t necessarily mean that LNDD “messed up” the original results from the point of view that they failed to follow proper procedures. And even if they did, it would be of no use to Landis in his case at CAS.

Larry October 23, 2007 at 7:20 pm

William, the EPO test is tricky. The latest TD from WADA on this test tries to set forth a uniform standard for the interpretation of these results, but this may be a case where reasonable minds may differ.

It’s also possible that the Ghent lab asked the Aussie lab for a second opinion. That appears to be something that WADA allows their labs to do.

Even still, it seems to me that if the “B” test results are inconclusive, then case closed. And there’s no way I can explain the delay in the handling of Mayo’s “B” sample. Somebody’s got some ‘splaining to do.

But as Judge Hue points out, we just don’t know enough at this point to reach any firm conclusions.

Rant October 23, 2007 at 7:31 pm

Larry,

It seems to me that what you say about Ghent asking the Aussie lab for another opinion may be what happened. That’s how I remember the news reports about the case, although I can’t find the links to those reports. I haven’t managed to locate WADA’s document laying out the requirement for a second lab to perform the tests, either, though I’m sure I saw it a few weeks back. It’s certainly not in the technical documents about the test, as you discovered.

I should have saved those articles back when I saw them the first time. As powerful as the Internet is, it’s not always so easy to find the information when you need it.

The waters that Mayo is in right now certainly sound murky right now. As Bill Hue said, there’s a lot we don’t know right now.

Howard October 24, 2007 at 9:11 am

This ‘Mayo clean’ thing looks like premature spin from the Spanish cycling authority. (Who appear to be very quick to shelve doping allegations.. especially when Spanish riders are involved).

In reality the ‘B’ sample result was “unreadable”, so it looks like if anyone has screwed up it is far more likely to be the lab testing the ‘B’ sample than the French lab who tested the ‘A’ samples…

http://www.lequipe.fr/Cyclisme/breves2007/20071023_130131Dev.html

Rant October 24, 2007 at 11:21 am

Howard,

As I said in a different comment elsewhere: Are the results really “unreadable” or “inconclusive”? I’m not sure we can draw a conclusion that either lab has screwed things up (though it wouldn’t surprise me much), especially given how complicated this test is said to be to perform and to interpret.

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